This study summarizes the knowledge about effects of bisphenol A (BPA) and its analogues on reproduction of pigs and some parameters of their offspring during period 2011-2020. Bisphenols are known as one of the most harmful environmental toxicants with endocrine-disrupting properties. One study in the reference period related to male reproductive system. Treatment with an antagonist of G-protein coupled estrogen receptor (GPER) – G15, and bisphenol A and its analogues, tetrabromobisphenol A (TBBPA) and tetrachromobisphenol A (TCBPA) diversely disrupted protein molecules controlling the biogenesis and function of microRNA in Leydig cells. Nine studies examined the effect of BPA, bisphenol S (BPS) or fluorene-9-bisphenol (BHPF) on female reproductive system. From the possible protective effect´s point of view seems to be perspective the administration of melatonin in BPA-exposed oocytes. Finally, two studies were found to evaluate the maternal exposure to BPA on offspring´s meat quality, muscle metabolism and oxidative stress. Administration of methyl donor improved antioxidant enzymes activity and reduced oxidative stress in piglets.

这项研究总结了有关双酚A（BPA）及其类似物对猪繁殖及其后代某些参数的影响的知识。双酚被公认为具有破坏内分泌特性的最有害的环境毒物之一。参考期的一项研究与男性生殖系统有关。用G蛋白偶联雌激素受体（GPER）– G15和双酚A及其类似物，四溴双酚A（TBBPA）和四色双酚A（TCBPA）的拮抗剂治疗，可破坏多种蛋白质分子，从而控制Leydig细胞中microRNA的生物发生和功能。九项研究检查了BPA，双酚S（BPS）或芴9-双酚（BHPF）对女性生殖系统的影响。从可能的保护作用的角度看，褪黑激素在暴露于BPA的卵母细胞中的应用是一个角度。最后，有两项研究评估了母体接触BPA的后代肉品质，肌肉代谢和氧化应激。甲基供体的施用改善了仔猪的抗氧化酶活性并降低了氧化应激。