The 3D printing apparatus in conventional inkjet and stereolithography systems is limited to continuous fabrication of a microsized three-dimensional hydrogel composed of multiple substances. We present a micro three-dimensional printing system by combining a polydimethylsiloxane microfluidic channel through which various fluids can flow into a micro two-dimensional particle generation system, and a single-axis stepper motor to control the thickness of each layer. The optimal channel designs for micro three-dimensional printing were set up through a physics simulation program and using the simulation analysis, the optimal microfluidic channel was fabricated. Through the system and channel, three-dimensional micropatterns and particles could be fabricated and the generated microparticles automatically collected by the washing flow in the channel. Zinc oxide nanoparticle materials transparent, biocompatible, and capable of absorbing ultraviolet light were added to the premixed photocurable solution used for the microparticle production, and thereby precise micro three-dimensional patterns and particles could be fabricated. In addition, by transporting a variety of fluids into the microfluidic channel, it was possible to create micro three-dimensional particles composed of heterogeneous materials.

传统的喷墨和立体光刻系统中的3D打印设备仅限于连续制造由多种物质组成的微型三维水凝胶。我们通过组合聚二甲基硅氧烷微流体通道和单轴步进电机来控制各个层的厚度，该系统通过各种流体可以流入微型二维颗粒生成系统，并结合了聚二甲基硅氧烷微流体通道。通过物理模拟程序建立了微三维打印的最佳通道设计，并通过仿真分析，制备了最佳的微流体通道。通过系统和通道，可以制造三维微图案和颗粒，并通过通道中的清洗流自动收集生成的微粒。将透明，生物相容且能够吸收紫外线的氧化锌纳米粒子材料添加到用于微粒生产的预混合光固化溶液中，从而可以制造出精确的三维立体图案和微粒。另外，通过将各种流体输送到微流体通道中，可以产生由异质材料组成的微观三维微粒。