Reinfection in endodontically treated teeth is linked to the complexity of the root canal system, which is problematic to reach with conventional disinfection methods. As plasma is expected to have the ability to sanitize narrow areas, the aim of this study was to analyze the effect of cold atmospheric pressure plasma (CAP) on Candida albicans in root canals of extracted human teeth. CAP was applied as mono treatment and in combination with standard endodontic disinfectants (sodium hypochlorite, chlorhexidine and octenidine). Disinfection efficiency was evaluated as reduction of the logarithm of colony forming units per milliliter (log₁₀ CFU/mL) supported by scanning electron microscopy as imaging technique. Plasma alone showed the highest reduction of log₁₀ CFU, suggesting the best disinfection properties of all tested agents.

中文翻译：

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大气压冷血浆和消毒剂对拔牙人牙根管中白色念珠菌的影响。

经牙髓治疗的牙齿的再感染与根管系统的复杂性有关，而传统的消毒方法很难做到这一点。由于血浆有望具有对狭窄区域进行消毒的能力，因此本研究的目的是分析冷大气压血浆（CAP）对拔出的人牙根管中白色念珠菌的影响。CAP可以单次使用，也可以与标准牙髓消毒剂（次氯酸钠，洗必泰和辛烯丁胺）联合使用。通过扫描电子显微镜作为成像技术，以每毫升菌落形成单位的对数减少（log ₁₀ CFU / mL）来评估消毒效率。仅血浆显示对数₁₀的最大减少 CFU，表明所有测试试剂的最佳消毒性能。