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Effects of fetal and maternal genotype on placentome morphology in sheep
Theriogenology ( IF 2.8 ) Pub Date : 2020-12-01 , DOI: 10.1016/j.theriogenology.2020.09.013
K A Vonnahme 1 , W J Arndt 2 , P P Borowicz 2 , J S Caton 2 , A T Grazul-Bilska 2 , D A Redmer 2 , L P Reynolds 2
Affiliation  

Both maternal and fetal genotypes contribute to conceptus development. The objective was to determine how placentome number, size, and type and fetal weight was influenced after reciprocal embryo transfer in Columbia and Romanov sheep. Reciprocal embryo transfer was conducted between Columbia and Romanov ewes where a single embryo was transferred into Romanov and Columbia recipients [Romanov embryo in a Romanov uterus (RinR, n = 9); Romanov embryo in a Columbia uterus (RinC, n = 7); Columbia embryo in a Columbia uterus (CinC, n = 8); Columbia embryo in a Romanov uterus (CinR, n = 4)]. On day 130 of gestation, fetuses were weighed and placentomes were morphologically typed, weighed, and measured. Regardless of maternal genotype, Romanov fetuses were smaller (P < 0.05) compared to Columbia fetuses. Moreover, CinC fetuses were larger (P < 0.05) than CinR fetuses. There was a tendency (P = 0.12) for a fetal by maternal genotype interaction on total placentome weight, but main effects were significant for fetal genotype (P = 0.04) and maternal genotype (P < 0.01). The number of Type A placentomes was greater than any other types. Type A placentomes had a greater (P < 0.05) contribution to total placentome weight within the Romanov uterus, or when associated with a Romanov fetus, than within the Columbia breed, in which placentome type was evenly distributed. The hypothesis that the Romanov uterus would limit the growth of a Columbia conceptus is accepted; however, the Romanov conceptus did not experience augmented growth when transferred into a Columbia uterus as predicted.

中文翻译:

胎儿和母体基因型对绵羊胎盘形态的影响

母体和胎儿基因型都有助于孕体发育。目的是确定哥伦比亚和罗曼诺夫绵羊在相互胚胎移植后如何影响胎盘数量、大小、类型和胎儿重量。在哥伦比亚和罗曼诺夫母羊之间进行了互惠胚胎移植,其中单个胚胎被转移到罗曼诺夫和哥伦比亚受者[罗曼诺夫子宫中的罗曼诺夫胚胎(RinR,n = 9);哥伦比亚子宫中的罗曼诺夫胚胎(RinC,n = 7);哥伦比亚子宫中的哥伦比亚胚胎(CinC,n = 8);罗曼诺夫子宫中的哥伦比亚胚胎 (CinR, n = 4)]。在妊娠第 130 天,对胎儿进行称重,并对胎盘进行形态分型、称重和测量。无论母体基因型如何,与哥伦比亚胎儿相比,罗曼诺夫胎儿都较小(P < 0.05)。此外,CinC 胎儿更大(P < 0. 05) 比 CinR 胎儿。母体基因型相互作用对胎盘总重量的胎儿有一种趋势(P = 0.12),但胎儿基因型(P = 0.04)和母体基因型(P < 0.01)的主要影响显着。A 型胎盘的数量多于其他任何类型。A 型胎盘对罗曼诺夫子宫内或与罗曼诺夫胎儿相关的总胎盘重量的贡献大于 (P < 0.05) 比哥伦比亚品种内的胎盘类型均匀分布。接受罗曼诺夫子宫会限制哥伦比亚孕胎生长的假设;然而,如预测的那样,当转移到哥伦比亚子宫时,罗曼诺夫孕体并没有经历增强的生长。12) 对于胎儿,母体基因型相互作用对胎盘总重量的影响,但对胎儿基因型 (P = 0.04) 和母体基因型 (P < 0.01) 的主要影响显着。A 型胎盘的数量多于其他任何类型。A 型胎盘对罗曼诺夫子宫内或与罗曼诺夫胎儿相关的总胎盘重量的贡献大于 (P < 0.05) 比哥伦比亚品种内的胎盘类型均匀分布。接受罗曼诺夫子宫会限制哥伦比亚孕胎生长的假设;然而,如预测的那样,当转移到哥伦比亚子宫时,罗曼诺夫孕体并没有经历增强的生长。12) 对于胎儿,母体基因型相互作用对胎盘总重量的影响,但对胎儿基因型 (P = 0.04) 和母体基因型 (P < 0.01) 的主要影响显着。A 型胎盘的数量多于其他任何类型。A 型胎盘对罗曼诺夫子宫内或与罗曼诺夫胎儿相关的总胎盘重量的贡献大于 (P < 0.05) 比哥伦比亚品种内的胎盘类型均匀分布。接受罗曼诺夫子宫会限制哥伦比亚孕胎生长的假设;然而,如预测的那样,当转移到哥伦比亚子宫时,罗曼诺夫孕体并没有经历增强的生长。A 型胎盘的数量多于其他任何类型。A 型胎盘对罗曼诺夫子宫内或与罗曼诺夫胎儿相关的总胎盘重量的贡献大于 (P < 0.05) 比哥伦比亚品种内的胎盘类型均匀分布。接受罗曼诺夫子宫会限制哥伦比亚孕胎生长的假设;然而,如预测的那样,当转移到哥伦比亚子宫时,罗曼诺夫孕体并没有经历增强的生长。A 型胎盘的数量多于其他任何类型。A 型胎盘对罗曼诺夫子宫内或与罗曼诺夫胎儿相关的总胎盘重量的贡献大于 (P < 0.05) 比哥伦比亚品种内的胎盘类型均匀分布。接受罗曼诺夫子宫会限制哥伦比亚孕胎生长的假设;然而,如预测的那样,当转移到哥伦比亚子宫时,罗曼诺夫孕体并没有经历增强的生长。接受罗曼诺夫子宫会限制哥伦比亚孕胎生长的假设;然而,如预测的那样,当转移到哥伦比亚子宫时,罗曼诺夫孕体并没有经历增强的生长。接受罗曼诺夫子宫会限制哥伦比亚孕胎生长的假设;然而,如预测的那样,当转移到哥伦比亚子宫时,罗曼诺夫孕体并没有经历增强的生长。
更新日期:2020-12-01
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