The conversion of the glycerophospholipid phosphatidic acid (PA) into diacylglycerol (DAG) is essential for the biosynthesis of membrane phospholipids and storage fats. Importantly, both PA and DAG can also serve signaling functions in the cell. The dephosphorylation of PA that yields DAG can be executed by two different classes of enzymes, Mg²⁺-dependent lipins and Mg²⁺-independent lipid phosphate phosphatases. Here, I will discuss the current status of research directed at understanding the roles of these enzymes in insect development and metabolism. Special emphasis will be given to studies in the model organism Drosophila melanogaster.

中文翻译：

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磷脂酸磷酸酶在昆虫发育和代谢中的不同作用。

甘油磷脂磷脂酸 (PA) 转化为二酰基甘油 (DAG) 对于膜磷脂和储存脂肪的生物合成至关重要。重要的是，PA 和 DAG 还可以在细胞中提供信号功能。产生 DAG 的 PA 去磷酸化可以通过两类不同的酶来执行，即 Mg ²⁺依赖性脂质和 Mg ²⁺非依赖性脂质磷酸酶。在这里，我将讨论旨在了解这些酶在昆虫发育和新陈代谢中的作用的研究现状。将特别强调对模式生物黑腹果蝇的研究。