Abstract Collagen (COL) membrane possesses poor mechanical properties and low surface hydrophilicity. In this paper, COL films were modified by graphene oxide (GO) and polydopamine (PDA), the COL–GO–PDA composite films were prepared. The interaction between the surface self-assembled PDA and the COL membrane modified with different concentrations of GO was studied. Membranes were studied systematically by Attenuated Total Reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) and mechanical properties. Besides the structural integrity was studied by X-ray diffraction (XRD), thermal stability including differential scanning calorimetry (DSC) and thermogravimetry (TG). The scanning electron microscopy (SEM) and surface water contact angle (WCA) were studied for surface condition and hydrophilicity of the material. In addition, the biological evaluation was carried out in vivo by MTT assay.

中文翻译：

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新型纳米材料氧化石墨烯改性胶原表面负载聚多巴胺的复合膜材料的表征及体外实验

摘要 胶原（COL）膜机械性能差，表面亲水性低。本文采用氧化石墨烯（GO）和聚多巴胺（PDA）对COL薄膜进行改性，制备了COL-GO-PDA复合薄膜。研究了表面自组装PDA与不同浓度GO修饰的COL膜之间的相互作用。通过衰减全反射-傅立叶变换红外光谱 (ATR-FTIR) 和机械性能系统地研究了膜。除了通过 X 射线衍射 (XRD) 研究结构完整性外，热稳定性还包括差示扫描量热法 (DSC) 和热重法 (TG)。扫描电子显微镜（SEM）和表面水接触角（WCA）研究了材料的表面状况和亲水性。此外，