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A comparative study on susceptibility, course of parasitemia, and pattern of infection with Trypanosoma evansi between different laboratory animals
Journal of Taibah University for Science ( IF 3.3 ) Pub Date : 2020-09-13 , DOI: 10.1080/16583655.2020.1816323
Al- Shaimaa M. Sadek 1
Affiliation  

This study investigated the susceptibility of eight different animal species (rat, mice, guinea pigs, hamsters, rabbits, sheep, goats, and chicken) experimentally infected with Trypanosoma evansi isolated from camels. In all laboratory animals, the number of trypanosomes was standardized according to the weight of the animal, and daily examination of the blood was conducted to assess the presence of trypanosomes to determine the prepatent period and the peak of parasitemia. Results suggested that mice and rats were the most susceptible laboratory animals to infection, whereas hamsters and guinea pigs displayed a certain degree of tolerance to infection. Rabbits exhibited a chronic course of infection, but the level of parasitemia was very low. In sheep and goats, trypanosomes were detectable only by subpassage to rats and mice, whereas all the chickens remained uninfected even with increasing doses of infection.



中文翻译:

不同实验动物之间伊万氏锥虫感染易感性,寄生虫病进程和感染方式的比较研究

这项研究调查了实验感染伊万氏锥虫的八种不同动物(大鼠,小鼠,豚鼠,仓鼠,兔子,绵羊,山羊和鸡)的敏感性与骆驼隔离。在所有实验动物中,锥虫体的数量根据动物的体重标准化,并每天进行血液检查以评估锥虫体的存在,以确定形成周期和寄生虫病高峰。结果表明,小鼠和大鼠是最容易受到感染的实验动物,而仓鼠和豚鼠对感染表现出一定程度的耐受性。兔子表现出慢性感染过程,但寄生虫血症水平很低。在绵羊和山羊中,锥虫只能通过对大鼠和小鼠的次传代而被检测到,而即使感染剂量增加,所有的鸡仍未受到感染。

更新日期:2020-09-13
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