The Mexican-Mestizo population arose following European contact with the Americas due to the admixture of principally Spaniards, Native Americans, and Africans around 500 years ago. Because the paternal lineage distribution of the Mexican population has been poorly investigated, this study inferred the haplogroups of ten populations based on 1859 haplotypes (Y-STR data) using two haplogroup predictor programs. In the Mexican population sample, we found predominantly European ancestry (50.1%), followed by Native American (32.5%), Eurasian (13.4%), African (2.1%), East African-South Eurasian (1.3%), and Asian (0.6%) ancestries. In general, our results support a contrary north-to-south gradient throughout the Mexican territory of European and Native-American ancestries, respectively. Moreover, the presence of West-European R1b and Sub-Saharan African E1b1a haplogroups agrees with historical and genetic data of gene flow during the European conquest. This study represents the effort to analyze these paternal lineages on a large scale by taking advantage of Y-STR haplotype data to determine the distribution and ancestry proportions in this country.

在欧洲与美洲接触之后，墨西哥-梅斯蒂佐（Mestizo）人口崛起，原因是大约500年前主要是西班牙人，美洲原住民和非洲人混杂在一起。由于对墨西哥人口的父系血统分布研究不多，因此本研究使用两个单倍群预测程序根据1859个单倍型（Y-STR数据）推断了十个人口的单倍群。在墨西哥人口样本中，我们发现主要是欧洲血统（50.1％），其次是美洲原住民（32.5％），欧亚（13.4％），非洲（2.1％），东非-南欧亚（1.3％）和亚洲（ 0.6％）的祖先。总的来说，我们的结果分别支持整个欧洲和美洲原住民的墨西哥领土从南北向相反的梯度。此外，西欧R1b和撒哈拉以南非洲E1b1a单倍体的存在与欧洲征服期间基因流的历史和遗传数据相吻合。这项研究代表了通过利用Y-STR单倍型数据来确定该国分布和血统比例的大规模分析这些父系的努力。