Background: 

COVID-19 disease has spread globally and was declared a pandemic on March 11, 2020, by the World Health Organization. On March 10, the State of Michigan confirmed its first 2 cases of COVID-19, and the number of confirmed cases has reached 47,182 as of May 11, 2020, with 4555 deaths.

Setting: 

Currently, little is known if patients living with HIV (PLWH) are at a higher risk of severe COVID-19 or if their antiretrovirals are protective. This study presents epidemiologic and clinical features of COVID-19 infected PLWH in Detroit, Michigan.

Methods: 

This is a case series that included 14 PLWH with laboratory-confirmed COVID-19 infection who were evaluated at Henry Ford Hospital in Detroit, Michigan, between March 20, 2020, and April 30, 2020.

Results: 

Fourteen PLWH were diagnosed with COVID-19. Twelve patients were men and 2 were women; 13 patients were virally suppressed. Eight patients were hospitalized, and 6 patients were told to self-quarantine at home after their diagnoses. Three patients who were admitted expired during their hospital stay. No patient required bilevel positive airway pressure or nebulizer use in the emergency department, and none developed acute respiratory distress syndrome, pulmonary embolism, deep venous thrombosis, or a cytokine storm while on therapy for COVID-19.

Conclusion: 

Although the clinical spectrum of COVID-19 among PLWH cannot be fully ascertained by this report, it adds to the data that suggest that HIV-positive patients with SARS-CoV-2 infection are not at a greater risk of severe disease or death as compared to HIV-negative patients.

中文翻译：

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描述性分析受COVID-19影响的HIV感染者

背景： 

COVID-19疾病已在全球蔓延，并于2020年3月11日被世界卫生组织宣布为大流行病。3月10日，密歇根州确认了首例2例COVID-19病例，截至2020年5月11日，确诊病例数达到47,182例，死亡4555例。

设置： 

目前，鲜为人知的是，HIV感染者（PLWH）患严重COVID-19的风险较高，还是他们的抗逆转录病毒药具有保护性。这项研究介绍了密歇根州底特律市COVID-19感染的PLWH的流行病学和临床特征。

方法： 

该案例系列包括2020年3月20日至2020年4月30日在密歇根州底特律的亨利·福特医院评估的14例实验室确诊COVID-19感染的PLWH。

结果： 

14名PLWH被诊断出患有COVID-19。男性12例，女性2例；13名患者被病毒抑制。八名患者住院，诊断后被告知六名患者在家进行自我隔离。三名入院患者在住院期间死亡。在急诊科中，没有患者需要双水平气道正压或雾化器使用，也没有在接受COVID-19治疗时出现急性呼吸窘迫综合征，肺栓塞，深静脉血栓形成或细胞因子风暴。

结论： 

尽管本报告无法完全确定PLWH中COVID-19的临床情况，但它补充了数据，表明与SARS-CoV-2感染有关的HIV阳性患者与重症患者相比，没有更大的患严重疾病或死亡的风险对HIV阴性的患者。