IgA and Th17 responses are pivotal for the control of Giardia infections. Eosinophils support IgA class switching, the survival of intestinal IgA⁺ plasma cells at steady state and can control Th17 activity in the small intestine. To see whether eosinophils regulate adaptive immune responses during giardiasis, we investigated Giardia muris infections in wild‐type BALB/c and eosinophil‐deficient ∆dblGATA‐1 mice.

中文翻译：

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嗜酸性粒细胞可用于调节贾第鞭毛虫感染中的IgA和Th17反应

IgA和Th17应答对于控制贾第鞭毛虫感染至关重要。嗜酸性粒细胞支持IgA类转换，稳定状态下肠IgA ⁺浆细胞的存活并可以控制小肠中Th17的活性。为了解嗜酸性粒细胞是否在贾第鞭毛虫病期间调节适应性免疫反应，我们调查了野生型BALB / c和嗜酸性粒细胞缺乏型ΔdblGATA-1小鼠的贾第鞭毛虫感染。