Gold nanoparticles combined with a polyphenolic glycoside (α-glucosylrutin) were prepared and applied for the selective detection of proteins. Glucosylrutin was coated onto gold nanoparticles with a particle size of 40 nm, without aggregates and color changes. The glucosylrutin-coated gold surface was preferentially adsorbed with concanavalin A, which has specificity against glucosides and mannosides. When the glucosylrutin-coated gold nanoparticles were mixed with concanavalin A, the color of the dispersion changed from red to reddish violet. The level of chromatic change was dependent on the concentration of concanavalin A. When other proteins (bovine serum albumin and peanut agglutinin) were added to the dispersion, no color change was observed. The molecular recognition site for detection of concanavalin A was the glycoside moiety, because the catechin-coated gold nanoparticles have no function in the detection of concanavalin A. Urchin-shaped glucosylrutin-coated gold nanoparticles were also useful for the visual sensing of concanavalin A.

制备了与多酚苷（α-葡萄糖基芦丁）结合的金纳米颗粒，并将其用于蛋白质的选择性检测。将葡糖基芦丁涂覆到粒径为40 nm的金纳米颗粒上，而没有聚集体和颜色变化。葡糖基芦丁涂覆的金表面优先被伴刀豆球蛋白A吸附，伴刀豆球蛋白A对葡糖苷和甘露糖苷具有特异性。当将涂覆有葡糖基芦丁的金纳米颗粒与伴刀豆球蛋白A混合时，分散体的颜色从红色变为红紫色。颜色变化的水平取决于伴刀豆球蛋白A的浓度。当将其他蛋白质（牛血清白蛋白和花生凝集素）添加到分散液中时，未观察到颜色变化。用于检测伴刀豆球蛋白A的分子识别位点是糖苷部分，