The solubility of cellulose has been studied as a function of composition in the binary mixture of 1,1,3,3-tetramethylguanidine and propionic acid. In amine-rich compositions, greater quantities of cellulose can be dissolved than in the equimolar composition, a.k.a. the protic ionic liquid [TMGH][OPr]. By applying a methodology of a short period of heating followed by cooling, similar concentrations of cellulose can be achieved in a much shorter time period. Finally, regeneration of cellulose from solution can be achieved by altering the acid:amine molar ratio. In comparison to cellulose regenerated from these solutions using water as an antisolvent, cellulose regenerated with propionic acid exhibit a lower crystallinity as inferred from x-ray diffractometry, but a greater average molecular weight as inferred from gel permeation chromatography.

已经研究了纤维素在1,1,3,3-四甲基胍和丙酸的二元混合物中的溶解度与组成的关系。与等摩尔组合物（也称为质子离子液体[TMGH] [OPr]）相比，在富含胺的组合物中可溶解更多量的纤维素。通过采用短时间加热然后冷却的方法，可以在短得多的时间内获得相似浓度的纤维素。最后，可以通过改变酸：胺的摩尔比来实现纤维素从溶液中的再生。与使用水作为抗溶剂从这些溶液中再生的纤维素相比，用丙酸再生的纤维素显示出较低的结晶度（如通过X射线衍射法推断的），但具有较大的平均分子量（如通过凝胶渗透色谱法推断的）。