The objective of this study is to prepare a novel mouthwash that contains Amorphous Calcium Phosphate nanoparticles (ACP-NPs) in a chitosan aqueous solution in order to prevent and treat the existing enamel decalcification around the brackets and gingivitis. ACP-NPs have been synthesized via a co-precipitation technique from the solution of ammonium hydrogen phosphate and calcium chloride, as well as the addition of sodium hydroxide for the adjustment of pH ∼ 8. Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), field emission scanning electron microscope (FESEM), Energy dispersive X-ray spectroscopy (EDX), and the Barrett–Joyner–Halenda (BJH) desorption have been performed on the samples. The ACP-NPs seemed to contain an initial particle size of less than 40 nm and the Ca/P ratio of 1.14. We have applied chitosan since it can function as the stabilizer, antibacterial, and anti-inflammatory and thus, prevent plaque, bad breath, and decrease gingivitis. Agar dilution has been utilized to assess the antibacterial or effectiveness of the prepared mouthwash. This particular mouthwash can be considered smart since it has the ability to increase the ion release at a carcinogenic pH 4, which is the significant timing when these ions are mostly needed and required to inhibit the caries. 

这项研究的目的是制备一种新颖的漱口水，该漱口水在壳聚糖水溶液中包含无定形磷酸钙纳米颗粒（ACP-NP），以预防和治疗托槽和牙龈炎周围的搪瓷脱钙现象。ACP-NPs是通过共沉淀技术从磷酸氢铵和氯化钙的溶液中合成的，并添加氢氧化钠以调节pH值约8。傅立叶变换红外（FTIR）光谱，X射线样品已进行了衍射（XRD），场发射扫描电子显微镜（FESEM），能量色散X射线光谱（EDX）和Barrett-Joyner-Halenda（BJH）解吸。ACP-NP似乎包含小于40 nm的初始粒径和1.14的Ca / P比。我们已经使用了壳聚糖，因为它可以起到稳定剂，抗菌和消炎的作用，因此可以预防牙菌斑，口臭和减少牙龈炎。琼脂稀释液已用于评估制备的漱口水的抗菌性或有效性。可以认为这种特殊的漱口水是明智的，因为它具有在致癌pH 4下增加离子释放的能力，这是最需要和需要抑制离子的重要时间。