Witko et al. describe poly(3‐hydroxyoctanoate) (PHO) films as a growth substrate for mouse embryonic fibroblast (MEF) cells, with a view to using them for medical applications. Surface characterization is carried out using atomic force microscopy, polarized light microscopy and force spectroscopy. Cells cultured on PHO exhibit thin densely spaced actin bundles, while the filaments are thicker but sparsely distributed on often‐used glass. Microtubular architecture analysis reveals thick and clearly separated microtubular bundles on glass whereas those on PHO take the form of a mesh of thin, densely arranged fibers. Migration of MEF cells on the PHO substrates is slower than on glass. (DOI: 10.1002/bip.23324)

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Witko等。为了描述将聚（3-羟基辛酸酯）（PHO）膜用作小鼠胚胎成纤维细胞（MEF）细胞的生长底物，其目的是将其用于医疗应用。使用原子力显微镜，偏振光显微镜和力光谱法进行表面表征。在PHO上培养的细胞表现出稀疏的密集肌动蛋白束，而细丝较粗，但稀疏分布在常用玻璃上。微管结构分析显示，玻璃上的微管束厚且清晰地分开，而PHO上的管束则是细密排列的细纤维网状。MEF细胞在PHO基底上的迁移比在玻璃上的迁移慢。（DOI：10.1002 / bip.23324）