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Mechanical properties and osteoblast proliferation of complex porous dental implants filled with magnesium alloy based on 3D printing.
Journal of Biomaterials Applications ( IF 2.9 ) Pub Date : 2020-09-11 , DOI: 10.1177/0885328220957902
Xuetao Zhang 1 , Jian Mao 1 , Yufeng Zhou 1 , Fangqiu Ji 2 , Xianshuai Chen 2
Affiliation  

In this paper, a complex porous dental implant with biodegradable magnesium alloy was designed based on selective laser melting (SLM). Finite element analysis (FEA) was used to simulate the stress distribution of dental implant and alveolar bone in two models of preliminary and later stages of implant. The stress concentration area of dental implants was found not in the porous structure, and the weak part of mechanical properties accords with the work requirements. The porous structure of dental implants can promote the function of cancellous bone in the process of conducting the stress of the dental implant, thus improving the bearing capacity of dental implants. In vitro fatigue experiments were carried out on the experimental samples produced by 3D printing. Through the cell contrast experiment, it was proved that the decomposed Mg2+ could reach the titanium surface smoothly through the porous structure and complete the proliferation of osteoblasts.



中文翻译:

基于 3D 打印的镁合金填充复杂多孔牙种植体的力学性能和成骨细胞增殖[J].

在本文中,基于选择性激光熔化(SLM)设计了一种具有可生物降解镁合金的复杂多孔牙种植体。采用有限元分析(FEA)模拟种植体前期和后期两种模型中种植体和牙槽骨的应力分布。牙种植体应力集中区不在多孔结构中,力学性能薄弱部分符合工作要求。种植体的多孔结构可以促进松质骨在传导种植体应力的过程中发挥作用,从而提高种植体的承载能力。体外对3D打印制作的实验样品进行疲劳实验。通过细胞对比实验证明,分解后的Mg 2+可以通过多孔结构顺利到达钛表面,完成成骨细胞的增殖。

更新日期:2020-09-11
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