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A Computed Tomographic Assessment of Osteitis of Sinus Bony Structures in Horses With Sinonasal Disorders
Frontiers in Veterinary Science ( IF 3.2 ) Pub Date : 2020-08-03 , DOI: 10.3389/fvets.2020.00627
Padraic M. Dixon , Coline Puidupin , Dewi Borkent , Tiziana Liuti , Richard J. M. Reardon

Background: Computed tomographic (CT) imaging has shown some horses with sinonasal diseases to have changes in their sinus bony structures. Scintigraphic and clinical evidence of sinus osteitis have also been reported. However, no study has objectively examined for the presence and degree of osteitis in equine sinonasal disease.

Objectives: To assess for the presence and extent of osteitis of sinus-related bony structures by examination of CT images of horses with clinically and sinoscopically confirmed unilateral sinonasal disease.

Study Design: Retrospective examination of CT images of horses with confirmed, mainly chronic (>2 month duration) unilateral sinus disease of different etiologies.

Methods: Bone thickness at designated sites of the maxillary bone (n = 3), frontal bone (n = 1), infraorbital canal (n = 2), and bony nasolacrimal duct (n = 1) were measured, as were the maximal diameters of the infraorbital canal and the bony nasolacrimal duct on both affected and control sides. Maxillary bone density (in Hounsfield Units) was also assessed bilaterally. Bone thickness was compared between affected and controlled sides using paired statistical tests.

Results: Bone was significantly thicker in the affected sinuses compared to the control sides at the three maxillary bone sites (all, P < 0.001) and at both infraorbital bone sites (both, P < 0.001), but not at the two most dorsal sites examined, i.e. frontal bone (P = 0.188) and bony nasolacrimal duct (P = −0.260) sites. Infraorbital canal and bony nasolacrimal duct diameters were significantly wider in the affected as compared to the control sides (P < 0.001 and P = 0.002, respectively). Maxillary bone density did not differ significantly between the affected (mean = 1,075 HU, SD = 230.01) and control (mean = 1,100, SD = 200.71) sides (t(58) = −1.03, P = 0.306).

Main Limitations: Possible variation in selecting measurement sites. Variation in the severity and chronicity of sinonasal disease between horses.

Conclusions: Osteitis and enlargement of paranasal bony structures commonly occurs in horses with sinonasal disease and can explain the clinical presence of ipsilateral diffuse soft tissue facial swelling, epiphora, and scintigraphic evidence of bone inflammation in sinonasal disease.



中文翻译:

鼻窦疾病马的窦骨结构骨炎的计算机断层扫描评估

背景:计算机断层扫描(CT)成像显示,一些患有鼻窦疾病的马的窦骨结构发生了变化。鼻窦炎的科学和临床证据也已有报道。但是,还没有客观研究马鼻窦疾病中骨炎的存在和程度的研究。

目标: 通过检查具有临床和鼻镜检查证实的单侧鼻窦疾病的马的CT图像,评估与窦有关的骨结构的骨炎的存在和程度。

学习规划: 对具有不同病因的已确认的主要是慢性(> 2个月持续时间)单侧鼻窦疾病的马进行CT图像的回顾性检查。

方法: 上颌骨指定部位的骨厚度(ñ = 3),额骨(ñ = 1),眶下管(ñ = 2),以及骨性鼻泪管(ñ= 1),同时测量患侧和对照侧的眶下管和骨性鼻泪管的最大直径。双边评估上颌骨密度(以Hounsfield单位)。使用配对的统计测试比较患侧和对照侧的骨厚度。

结果: 与三个上颌骨部位的对照侧相比,患鼻窦的骨明显较厚(所有, P <0.001)和在眶下两个骨部位(两个 P <0.001),但不是在检查的两个最背面的部位,即额骨(P = 0.188)和骨性鼻泪管(P= −0.260)网站。与对照侧相比,患部的眶下管和骨性鼻泪管直径明显更宽(P <0.001并且 P分别为0.002)。患侧(平均值= 1,075 HU,SD = 230.01)和对照(平均值= 1,100,SD = 200.71)之间的上颌骨密度没有显着差异(Ť(58) = −1.03,P = 0.306)。

主要局限性:选择测量位置时可能会有变化。马之间鼻窦疾病严重程度和慢性的变化。

结论: 骨炎和鼻旁骨结构的增大通常发生在鼻窦疾病的马匹中,并且可以解释鼻窦疾病中同侧弥漫性软组织面部肿胀,足溢和闪烁显像的临床证据。

更新日期:2020-09-11
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