Lamb weight at 8 months of age is an important trait in the sheep industry in terms of the onset of puberty around this age; however, knowledge of its effective genetic factors is limited. Therefore, a GWAS using the 50K SNP‐Chip was performed on 96 Baluchi sheep to identify the genomic regions associated with 8‐month weight. The results of the present study revealed five SNPs on chromosomes 4, 14 and 16 at 5% chromosome‐wide significance level, jointly accounting for 0.95% of total genetic variance. Four genes – MTPN, HYDIN, LRGUK and ZFP90 – were found in 50 kb intervals around the significant SNPs, of which MTPN is involved in regulation of skeletal muscle growth. Our results may provide a new vision to identify the genomic regions affecting growth traits in sheep.

中文翻译：

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全基因组关联研究显示，五个SNP影响绵羊的8个月体重。

就这个年龄左右的青春期开始而言，8个月大的羔羊体重是绵羊产业的重要特征。但是，对其有效遗传因素的了解是有限的。因此，对96头Bal鱼进行了使用50K SNP芯片的GWAS，以鉴定与8个月体重相关的基因组区域。本研究的结果表明，在4、14和16号染色体上有5个SNP，其全染色体显着性水平为5％，共同占总遗传变异的0.95％。在重要的SNP周围以50 kb的间隔发现了四个基因-MTPN，HYDIN，LRGUK和ZFP90，其中MTPN参与骨骼肌生长的调节。我们的结果可能为鉴定影响绵羊生长性状的基因组区域提供新的视野。