A new probe RB-CR for the detection of Cr³⁺ was constructed based on the conjugation between rhodamine B and phenylthiourea. The Cr³⁺ could trigger opening of the rhodamine spirolactam of RB-CR upon complexation selectively, sensitively and rapidly, resulting in a pronounced enhancement of absorption and fluorescence signal. Further fluorescence imaging study has suggested that RB-CR could be applied as a probe for Cr³⁺ surveillance in living HepG2 cells with low cytotoxicity, which provide us the feasibility of exploring the Cr³⁺ recognition process by the turn-on fluorescence response.

中文翻译：

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红色开启荧光探针可快速，灵敏地检测活细胞中的Cr3 +。

基于若丹明B与苯硫脲的结合，构建了一种用于检测Cr ³⁺的新型探针RB-CR。Cr ³⁺可以选择性，灵敏和快速地络合，从而触发RB-CR的若丹明螺内酰胺的打开，从而显着增强吸收和荧光信号。进一步的荧光成像研究表明，RB-CR可以用作低细胞毒性活HepG2细胞中Cr ³⁺监测的探针，这为我们提供了通过开启荧光反应探索Cr ³⁺识别过程的可行性。