Integrated multi trophic aquaculture (IMTA) is well developed in seawater, while the only suitable organisms for bioremediation in freshwater are bivalves. The aim of this research has been to investigate a novel system, based on freshwater bivalves integrated with rainbow trout, for the bioremediation of inland aquaculture systems. The Unionid species selected for the experiments was Sinanodonta woodiana. Five mesocosm experiments were conducted to evaluate the efficiency of mussels in filtering the total bacteria and Aeromonas hydrophila, as well as their clearance efficiency on trout farm wastewater. The temperatures, dissolved oxygen, nitrates, and phosphates were monitored and were all within the physiological tolerance range of the species in all the experiments. The feasibility of bioremediation with S. woodiana in trout farming has thus been demonstrated, and among the tested rearing densities (3.75; 7.5; 15; 30 and 60 kg m⁻³) that of 7.5 kg m⁻³ was found to be optimal. The net reduction of the total bacterial concentration was as much as 72%, while that of A. hydrophila reached a level of 95–98%. No relevant effects of the mussels on particulate suspended material or sedimented material was observed, regardless of the temperature. The efficiency of freshwater bivalves in reducing the bacterial load, in particular toward A. hydrophila, indicates a bioremediation system with the possibility of interesting applications on inland fish farms, and as a biotechnological tool against the diffusion of antibiotic resistance in aquaculture.

综合多营养水产养殖（IMTA）在海水中非常发达，而在淡水中唯一适合生物修复的生物是双壳类。这项研究的目的是研究一种基于淡水双壳类动物和虹鳟鱼的新型系统，用于内陆水产养殖系统的生物修复。选择用于实验的无性系物种是Sinanodonta woodiana。进行了五次介观试验，以评估贻贝过滤总细菌和嗜水气单胞菌的效率以及它们对鳟鱼养殖场废水的清除效率。在所有实验中，监测温度，溶解氧，硝酸盐和磷酸盐，并且都在该物种的生理耐受范围内。与生物修复的可行性S.蚌在鳟鱼养殖因此已经证明，与所测试的饲养密度中（3.75; 7.5; 15; 30和60公斤米^-3），其为7.5公斤米^-3被发现是最佳的。总细菌浓度的净减少是多达72％，而的嗜水气单达到95-98％的水平。不论温度如何，都没有观察到贻贝对颗粒状悬浮物或沉淀物的相关影响。淡水双壳类在减少细菌负载时的效率，尤其是朝向嗜水，指示与内陆鱼类养殖场有趣的应用的可能性生物修复系统，并作为对在水产养殖中的抗生素抗性的扩散的生物技术工具。