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Evolutionary Genomics of High Fecundity.
Annual Review of Genetics ( IF 11.1 ) Pub Date : 2020-11-23 , DOI: 10.1146/annurev-genet-021920-095932
Bjarki Eldon 1
Affiliation  

Natural highly fecund populations abound. These range from viruses to gadids. Many highly fecund populations are economically important. Highly fecund populations provide an important contrast to the low-fecundity organisms that have traditionally been applied in evolutionary studies. A key question regarding high fecundity is whether large numbers of offspring are produced on a regular basis, by few individuals each time, in a sweepstakes mode of reproduction. Such reproduction characteristics are not incorporated into the classical Wright–Fisher model, the standard reference model of population genetics, or similar types of models, in which each individual can produce only small numbers of offspring relative to the population size. The expected genomic footprints of population genetic models of sweepstakes reproduction are very different from those of the Wright–Fisher model. A key, immediate issue involves identifying the footprints of sweepstakes reproduction in genomic data. Whole-genome sequencing data can be used to distinguish the patterns made by sweepstakes reproduction from the patterns made by population growth in a population evolving according to the Wright–Fisher model (or similar models). If the hypothesis of sweepstakes reproduction cannot be rejected, then models of sweepstakes reproduction and associated multiple-merger coalescents will become at least as relevant as the Wright–Fisher model (or similar models) and the Kingman coalescent, the cornerstones of mathematical population genetics, in further discussions of evolutionary genomics of highly fecund populations.

中文翻译:


高繁殖力的进化基因组学。

自然高度繁殖力的人口比比皆是。这些范围从病毒到gadid。许多高繁殖力人口在经济上很重要。高繁殖力种群与传统上用于进化研究的低繁殖力生物形成了重要对比。有关高繁殖力的一个关键问题是,是否定期以抽奖方式繁殖少量个体定期繁殖大量后代。此类繁殖特征未纳入经典的Wright-Fisher模型,种群遗传学的标准参考模型或类似类型的模型中,在该模型中,每个个体相对于种群数量只能产生少量后代。抽奖活动繁殖的人口遗传模型的预期基因组足迹与莱特-费舍尔模型的预期基因组足迹有很大不同。紧迫的关键问题涉及确定基因组数据中抽奖活动复制的足迹。全基因组测序数据可用于区分抽奖活动复制产生的模式与根据Wright-Fisher模型(或类似模型)发展的种群的种群增长模式。如果抽奖再现的假设不能被否定,那么抽奖再现和相关的多合并联盟的模型将至少与Wright-Fisher模型(或类似模型)和Kingman联盟(数学种群遗传学的基石),

更新日期:2020-11-25
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