Effects of dietary Original XPC (XPC) on 17 selected blood variables in commercial layer pullets challenged with the virulent, low-passage R strain of Mycoplasma gallisepticum (RlowMG) were investigated. Hy-Line W-36 pullets sourced from M. gallisepticum-clean layer breeders were fed a basal diet with XPC (1.25 kg/metric ton) or without from hatch until 12 wk of age (woa). At 8 and 10 woa, half of the birds in each dietary treatment were challenged with RlowMG. Blood samples were taken immediately before the initial RlowMG challenge at 8 woa and again at 12 woa (4 wk after challenge). At 8 woa, blood pH was lower and glucose concentration was higher in the preassigned challenge treatment groups. At 12 woa, the concentration of oxygen dissolved in the blood was significantly lower in the RlowMG-challenged group than the unchallenged group of birds regardless of dietary treatment. The RlowMG challenge significantly increased blood carbon dioxide partial pressure, calcium, sodium, anion gap, osmolality, glucose, and corticosterone levels but significantly decreased blood oxygen partial pressure, oxyhemoglobin concentration, concentration of oxygen dissolved in the blood, chloride, and pH levels. Because blood pH and glucose concentration at 8 woa were examined before challenge, their baseline values were biased with respect to challenge treatment before treatment was applied. However, the lack of a significant main effect due to diet at 8 woa for blood pH and glucose concentration, along with the other 15 blood variables, indicate that the baseline data with respect to dietary treatment were unbiased, allowing for real dietary effects to be accurately assessed. In conclusion, layer pullets challenged with RlowMG undergo a stress response associated with changes in various physiological blood variables, and a decrease in pH and increase in carbon dioxide partial pressure, in association with a lack of change in bicarbonate, indicates that the stress response caused by the RlowMG challenge was associated with respiratory acidosis. Nevertheless, feeding XPC did not influence the effects of challenge treatment on these postchallenge physiological blood values.

中文翻译：

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日粮原始XPC对鸡毒支原体攻击的蛋鸡选择血液变量的影响。

研究了日粮原始XPC（XPC）对商品鸡种中17种选择的血液变量的影响，这些鸡种受到鸡毒支原体（RlowMG）的低通量R毒力的挑战。将来源于鸡败血支原体清洁种鸡的Hy-Line W-36母鸡饲喂XPC（1.25千克/公吨）或不孵化的基础饲料，直到12周龄（窝）。在8和10时，每次饮食处理中有一半的家禽受到RlowMG的攻击。在首次RlowMG攻击之前立即以8 woa和12 woa（攻击后4 wk）采集血样。预先设定的挑战治疗组在8 woa时，血液pH值较低，而葡萄糖浓度较高。12点，不管饮食如何，RlowMG挑战组的血液中溶解氧的浓度显着低于未挑战组。RlowMG挑战显着增加了血液中的二氧化碳分压，钙，钠，阴离子间隙，重量克分子渗透压浓度，葡萄糖和皮质酮水平，但显着降低了血液氧分压，氧合血红蛋白浓度，溶解在血液中的氧浓度，氯化物和pH值。因为在挑战前检查了8 woa的血液pH和葡萄糖浓度，所以在应用治疗之前，它们的基线值相对于挑战治疗有偏差。但是，由于饮食对血液pH值和葡萄糖浓度为8 woa，以及其他15种血液变量，缺乏明显的主要作用，指出饮食治疗的基线数据是无偏见的，从而可以准确评估实际饮食效果。总之，用RlowMG攻击的蛋鸡会经历与各种生理血液变量变化有关的应激反应，而pH值的降低和二氧化碳分压的增加与碳酸氢盐的变化缺乏相关，表明应激反应引起了由RlowMG挑战引起的与呼吸性酸中毒有关。尽管如此，喂养XPC并没有影响挑战治疗对这些挑战后生理血值的影响。受到RlowMG攻击的蛋鸡经历了与各种生理血液变量的变化相关的应激反应，pH降低和二氧化碳分压的升高，与碳酸氢盐的变化缺乏相关，表明由RlowMG引起的应激反应挑战与呼吸性酸中毒有关。尽管如此，喂养XPC并没有影响挑战治疗对这些挑战后生理血值的影响。受到RlowMG攻击的蛋鸡经历了与各种生理血液变量的变化相关的应激反应，pH降低和二氧化碳分压的升高，与碳酸氢盐的变化缺乏相关，表明由RlowMG引起的应激反应挑战与呼吸性酸中毒有关。尽管如此，喂养XPC并没有影响挑战治疗对这些挑战后生理血值的影响。