There is a need for an in-depth understanding of the impact of PrEP on users’ sexual health and behaviour, beyond the focus on ‘risk’. This mixed-method study was part of a Belgian PrEP demonstration project following 200 men who have sex with men (MSM) for at least 18 months. Taking a grounded-theory approach, 22 participants were interviewed and their transcripts analysed. The preliminary analysis guided the analysis of the questionnaire data. Overall, PrEP improved sexual health. Participants felt better protected against HIV, which enabled them to change their sexual behaviour. The reduction in condom use was moderated by interviewees’ attitudes towards the risk for other STIs. Other changes included having more anal sex and experimentation with new sexual behaviours. While PrEP empowers MSM in taking care of their sexual health, comprehensive sexual health counselling is crucial to provide care for users who feel less in control over their sexual health.

除了关注“风险”以外，还需要深入了解PrEP对使用者性健康和行为的影响。这项混合方法研究是比利时PrEP示范项目的一部分，该项目针对200名与男性发生性关系（MSM）至少18个月的男性。采取扎根理论的方法，对22名参与者进行了采访并分析了他们的笔录。初步分析指导了问卷数据的分析。总体而言，PrEP改善了性健康。与会者感到更好地受到了艾滋病毒的保护，这使他们能够改变自己的性行为。受访者对其他性传播感染风险的态度缓解了避孕套使用的减少。其他变化包括更多的肛交和尝试新的性行为。虽然PrEP授权MSM维护其性健康，