Although numerous studies investigated the effect of UASMS2 polymorphism in leptin gene on cattle production, a consensus has not yet been reached. Therefore, we reviewed and meta-analyzed the effects of UASMS2 on cattle. We searched potentially relevant studies from seven databases (to December 25, 2019). Standard mean difference along with 95% confidence intervals was calculated to assess the strength of association through the random-effects model. Six published articles containing 1378 cattle samples were included in our meta-analysis. We found UASMS2 was not related to carcass weight, dressing percentage and loin muscle area in the recessive genetic model, but there was a significant association between UASMS2 and average daily weight gain, dry matter intake, body weight, marbling score, and backfat thickness. This meta-analysis indicated that UASMS2 was associated with growth and meat quality traits of cattle, implying that this SNP can be used reliably in beef cattle breeding. This study may provide valuable information on improving beef yield and quality in cattle production.

中文翻译：

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瘦素基因UASMS2多态性与牛生长、胴体和肉质性状的关联：荟萃分析。

尽管许多研究调查了瘦素基因中UASMS2多态性对牛生产的影响，但尚未达成共识。因此，我们回顾和荟萃分析了 UASMS2 对牛的影响。我们从七个数据库（至 2019 年 12 月 25 日）中搜索了可能相关的研究。计算标准均值差和 95% 置信区间以通过随机效应模型评估关联强度。我们的荟萃分析包含六篇已发表的文章，其中包含 1378 份牛样本。我们发现，在隐性遗传模型中，UASMS2 与胴体重量、屠宰率和腰部肌肉面积无关，但 UASMS2 与平均日增重、干物质摄入量、体重、大理石花纹分数和背膘厚度之间存在显着关联。该荟萃分析表明，UASMS2 与牛的生长和肉质性状相关，这意味着该 SNP 可以可靠地用于肉牛育种。该研究可能为提高肉牛生产中的牛肉产量和质量提供有价值的信息。