当前位置: X-MOL 学术Front. Mol. Biosci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Can CRISPR/Cas Technology Be a Felicitous Stratagem Against the COVID-19 Fiasco? Prospects and Hitches
Frontiers in Molecular Biosciences ( IF 5 ) Pub Date : 2020-08-19 , DOI: 10.3389/fmolb.2020.557377
Rocktotpal Konwarh

The current global debacle of COVID-19, spelled by SARS-CoV-2 needs no elaboration. With incessant and constantly clambering number of deaths across various nations, the need of the hour is to develop readily deployable, fast, affordable detection assays and kits, yielding precise and consistent results as well as timely availability of efficacious anti-SARS-CoV-2 strategies to contain it. Conventionally employed real time PCR based technique for detection of the virus suffers from a couple of handicaps. Amongst other approaches, CRISPR based technology has ushered in new hopes. Recent efforts have been directed toward developing CRISPR/Cas based low-cost, rapid detection methods as well as development of one-pot assay platforms. The plausible application of CRISPR-Cas system to counteract the viral assault has also been assessed. The write up in this article mirrors the current status, the prospects and the practical snags of CRISPR/Cas technology for the detection and inactivation of the novel corona virus, SARS-CoV-2.



中文翻译:

CRISPR / Cas技术能否成为对抗COVID-19惨败的绝妙战略?前景与障碍

由SARS-CoV-2拼写的当前全球COVID-19崩溃无需详述。由于各个国家的死亡人数不断增加,因此需要开发易于部署,快速,负担得起的检测方法和试剂盒,以产生精确一致的结果,并及时提供有效的抗SARS-CoV-2控制它的策略。传统上使用的基于实时PCR的技术来检测病毒有两个障碍。在其他方法中,基于CRISPR的技术带来了新的希望。最近的努力已针对开发基于CRISPR / Cas的低成本,快速检测方法以及开发一锅测定平台。还评估了CRISPR-Cas系统抵消病毒攻击的合理应用。

更新日期:2020-09-10
down
wechat
bug