This study introduces a modeling method for a supermolecular structure of microtubules for the development of a force generation material using motor proteins. 3D imaging by confocal laser scanning microscopy (CLSM) was used to obtain 3D volume density data. The density data were then interpreted by a set of cylinders with the general-purpose 3D modeling software Blender, and a 3D network structure of microtubules was constructed. Although motor proteins were not visualized experimentally, they were introduced into the model to simulate pulling of the microtubules toward each other to yield shrinking of the network, resulting in contraction of the artificial muscle. From the successful force generation simulation of the obtained model structure of artificial muscle, the modeling method introduced here could be useful in various studies for potential improvements of this contractile molecular system.

中文翻译：

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通过共聚焦显微镜成像对微管丝网结构进行建模。

这项研究介绍了一种微管的超分子结构的建模方法，用于利用运动蛋白开发力产生材料。共聚焦激光扫描显微镜（CLSM）进行的3D成像用于获得3D体积密度数据。然后用通用3D建模软件Blender用一组圆柱体解释密度数据，并构建微管的3D网络结构。尽管无法通过实验观察到运动蛋白，但将它们引入模型中以模拟微管彼此之间的拉动，从而使网络收缩，从而导致人造肌肉收缩。通过成功生成的仿真肌肉模型结构的力生成模拟，