Endometriosis is a chronic inflammatory disease defined as the presence of endometrial tissue outside the uterus that causes pelvic pain and infertility. We used the Global Burden of Disease Study (GBD) 2017 to comprehensively analyze the burden of endometriosis between 1990 and 2017. DisMod‐MR 2.1 was used to estimate the incidence and prevalence in some countries/territories with sparse or absent data. Annual percent changes were calculated to quantify endometriosis burden estimate trends. Furthermore, the sociodemographic index (SDI) was used to assess the relationship between endometriosis burden estimates and development level. Between 1990 and 2017, endometriosis age‐standardized incidence and prevalence and years of life lived with disability (YLDs) decreased globally by 0.21% (95% confidence interval (CI): −0.23% to −0.20%), 0.29% (95% CI: −0.31% to −0.28%), and 0.28% (95% CI: −0.30% to −0.27%) per year, respectively. Apart from the high SDI quintiles with increasing trends of endometriosis incidence rate, prevalence rate, and YLDs, decreasing trends were observed in all SDI quintiles for all burden estimates. In conclusion, it appears that all endometriosis burden estimates have decreased globally between 1990 and 2017. However, these results are based on limited data and highlight the need for increased data collection on the incidence and prevalence of endometriosis.

中文翻译：

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1990 年至 2017 年全球、区域和国家子宫内膜异位症趋势

子宫内膜异位症是一种慢性炎症性疾病，定义为子宫外子宫内膜组织的存在，导致盆腔疼痛和不孕。我们使用 2017 年全球疾病负担研究 (GBD) 来全面分析 1990 年至 2017 年间子宫内膜异位症的负担。 DisMod-MR 2.1 用于估计一些数据稀少或缺乏数据的国家/地区的发病率和患病率。计算年度百分比变化以量化子宫内膜异位症负担估计趋势。此外，社会人口指数（SDI）用于评估子宫内膜异位症负担估计与发育水平之间的关系。1990 年至 2017 年间，子宫内膜异位症年龄标准化发病率和患病率以及残疾寿命 (YLD) 在全球范围内下降了 0.21%（95% 置信区间 (CI)：-0.23% 至 -0.20%）、0.29%（95%） CI：-0.31% 至 -0.28%）和 0.28%（95% CI：-0.30% 至 -0.27%）每年。除了随着子宫内膜异位症发病率、患病率和 YLD 增加趋势的高 SDI 五分位数，在所有负担估计的所有 SDI 五分位数中都观察到下降趋势。总之，1990 年至 2017 年间，全球所有子宫内膜异位症负担估计值似乎都在下降。 然而，这些结果基于有限的数据，并强调需要增加关于子宫内膜异位症的发病率和患病率的数据收集。