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Evaluation of pediatric patients in new-onset seizure clinic (NOSc)
Epilepsy & Behavior ( IF 2.6 ) Pub Date : 2020-11-01 , DOI: 10.1016/j.yebeh.2020.107428
Seunghyo Kim 1 , Ton DeGrauw 2 , Anne T Berg 3 , Kristen B Hass 2 , Sookyong Koh 2
Affiliation  

AIM We evaluated the clinical and demographic features of children presenting with unprovoked seizures at a regional new-onset seizure clinic (NOSc). METHODS We retrospectively reviewed charts of 492 consecutive patients evaluated in the NOSc at the Childrne's Healthcare of Atlanta RESULTS: Nonepileptic events (NEE) were diagnosed in 102 (24%) and epileptic seizures in the remaining 326 (76%). Patients with NEE were younger than patients with epileptic seizure (5.0 vs. 7.4 years). Except for headache which occurred more frequently in NEE (14% vs. 6%), frequencies of comorbidities were similar in groups with NEE and epileptic seizure. Electroencephalogram (EEG) was performed in 98%, and finding was abnormal in 51%. Brain magnetic resonance imaging (MRI) was performed in 55%, and finding was abnormal in 15%. An electroclinical epilepsy syndrome was diagnosed in 42%. Antiseizure medication was started in 25% with first seizure and in 77% with recurrent seizures. INTERPRETATION For children with newly-presenting seizures, a regional NOSc provided efficient, timely diagnosis and appropriate evaluations and treatment. Timely recognition of NEE resulted in fewer unnecessary evaluations and treatment for a quarter of referred patients whereas identification of the specific types of seizures and epilepsy allowed appropriate use, including deferral, of neuroimaging and guided treatment selection.

中文翻译:

新发癫痫门诊 (NOSc) 儿科患者的评估

目的 我们评估了在地区性新发癫痫诊所 (NOSc) 出现无端癫痫发作的儿童的临床和人口统计学特征。方法 我们回顾性地回顾了亚特兰大 Childrne's Healthcare 在 NOSc 中评估的 492 名连续患者的图表 结果:102 名 (24%) 被诊断为非癫痫事件 (NEE),其余 326 名 (76%) 被诊断为癫痫发作。NEE 患者比癫痫发作患者年轻(5.0 岁与 7.4 岁)。除了在 NEE 中更频繁发生的头痛(14% 对 6%),NEE 和癫痫发作组的合并症频率相似。98% 的患者进行了脑电图 (EEG),51% 的患者发现异常。55% 的患者进行了脑磁共振成像 (MRI),15% 的患者发现异常。42% 的患者被诊断为电临床癫痫综合征。25% 的首次癫痫发作和 77% 的复发性癫痫发作开始使用抗癫痫药物。解释 对于新出现癫痫发作的儿童,区域性 NOSc 提供了有效、及时的诊断以及适当的评估和治疗。及时识别 NEE 减少了四分之一转诊患者不必要的评估和治疗,而识别特定类型的癫痫发作和癫痫允许适当使用(包括推迟)神经影像学和指导治疗选择。及时诊断和适当的评估和治疗。及时识别 NEE 减少了四分之一转诊患者不必要的评估和治疗,而识别特定类型的癫痫发作和癫痫允许适当使用(包括推迟)神经影像学和指导治疗选择。及时诊断和适当的评估和治疗。及时识别 NEE 减少了四分之一转诊患者不必要的评估和治疗,而识别特定类型的癫痫发作和癫痫允许适当使用(包括推迟)神经影像学和指导治疗选择。
更新日期:2020-11-01
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