The transplantation of healthy hematopoietic stem cells (HSCs) contained in the bone marrow is a frontline treatment option for hematopoietic diseases. Detailed analysis of post-transplant HSC kinetics is crucial as the initial engraftment of HSCs influences prognosis. Dong et al. have explored the dynamic change in HSC cell fate upon bone marrow transplantation through the utilization of single-cell transcriptomic analysis.

中文翻译：

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骨髓移植动力学：当祖细胞膨胀发生时。

骨髓中健康的造血干细胞（HSC）的移植是造血疾病的一线治疗选择。移植后HSC动力学的详细分析至关重要，因为HSC的初始植入会影响预后。董等。通过利用单细胞转录组学分析，探索了骨髓移植后HSC细胞命运的动态变化。