Abstract Cyclohexane and sec-butyl alcohol are widely used in the pharmaceutical and chemical industries. The separation of cyclohexane/sec-butyl alcohol/water azeotropic mixture is of great significance for mitigating environmental risk, recycling solvents, and maintaining developmental sustainability. Based on the COSMO-SAC model, the infinite dilution activity coefficients of the components were calculated, and the final solvent was further obtained by relative volatility and solvent power screening. Taking the total annual cost as the objective function, the extractive distillation process is optimized based on a sequential iterative optimization algorithm. To further reduce the process energy consumption, several energy-saving processes were explored. Energy-saving processes are compared in terms of total annual cost, CO2 emissions, and thermodynamic efficiency. It was found that the total annual cost and thermodynamic efficiency of the processes show an increasing trend, while CO2 emissions show a decreasing trend. The results of stage-exergy indicate that the processes with heat pump are relatively small. The heat pump combined with the thermal coupling extractive distillation process exhibits better thermoeconomic and environmental performance. It provides theoretical guidance for improving the separation and recovery of value organics and energy-saving optimization of processes, which conforms to the theme of sustainable and environmental development.

中文翻译：

---

基于热经济与环境分析的热耦合萃取精馏结合热泵回收废水中有机物的节能研究

摘要 环己烷和仲丁醇广泛用于制药和化工行业。环己烷/仲丁醇/水共沸混合物的分离对于减轻环境风险、回收溶剂和保持发展可持续性具有重要意义。基于COSMO-SAC模型，计算各组分的无限稀释活度系数，通过相对挥发度和溶解力筛选进一步得到最终溶剂。以年总成本为目标函数，基于顺序迭代优化算法对萃取精馏过程进行优化。为了进一步降低工艺能耗，探索了几种节能工艺。根据年度总成本、二氧化碳排放量、和热力学效率。结果表明，这些过程的年总成本和热力学效率呈上升趋势，而 CO2 排放呈下降趋势。阶段火用的结果表明，热泵过程相对较小。热泵结合热耦合萃取精馏工艺表现出更好的热经济和环境性能。为提高有价有机物的分离回收和工艺的节能优化提供了理论指导，符合可持续发展和环境发展的主题。阶段火用的结果表明，热泵过程相对较小。热泵结合热耦合萃取精馏工艺表现出更好的热经济和环境性能。为提高有价有机物的分离回收和工艺的节能优化提供了理论指导，符合可持续发展和环境发展的主题。阶段火用的结果表明，热泵过程相对较小。热泵结合热耦合萃取精馏工艺表现出更好的热经济和环境性能。为提高有价有机物的分离回收和工艺的节能优化提供了理论指导，符合可持续发展和环境发展的主题。