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Homogeneous catalytic hydrogenation of lipids in aqueous dispersions and bacterial cell membranes with an efficient water-soluble Pd(II)-sulfosalan catalyst, Na2[Pd(HSS)]
Catalysis Communications ( IF 3.7 ) Pub Date : 2020-09-10 , DOI: 10.1016/j.catcom.2020.106153
Réka Gombos , Szilvia Bunda , Brigitta Nagyházi , Ferenc Joó

The recently synthesized water-soluble Na2[Pd(HSS)] (Na2HSS = hydrogenated sulfonated salen) was shown to be a non-toxic, active catalyst for modification of model and biomembranes by homogeneous catalytic hydrogenation. Hydrogenation of the unsaturated fatty acyl residues in soy-bean lecithin liposomes and in biomembranes of intact Pseudomonas putida F1 cells was accompanied by substantial cis-trans isomerization around the Cdouble bondC double bonds. The hydrogenations could be run in aqueous media under mild conditions (25 °C, 1 bar H2). Partial saturation (up to 10% conversion) of the membrane lipids of P. putida F1 did not damage the cells.



中文翻译:

用高效水溶性Pd(II)-磺基磺脲催化剂Na 2 [Pd(HSS)]对脂质在水分散液和细菌细胞膜中进行均相催化加氢

最近合成的水溶性Na 2 [Pd(HSS)](Na 2 HSS =氢化磺化塞伦)被证明是一种无毒的,通过均相催化氢化改性模型和生物膜的活性催化剂。在大豆卵磷脂脂质体和在完整的生物膜的不饱和脂肪酰残基的氢化恶臭假单胞菌F1细胞是伴随着相当大的顺式-反式以C异构化双键C双键。氢化反应可以在温和的条件下(25°C,1 bar H 2)在水性介质中进行。恶臭假单胞菌F1的膜脂的部分饱和(最高10%的转化率)没有破坏细胞。

更新日期:2020-09-10
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