The serum hormone concentrations were studied in a group of male F1 (C57BL/6×DBA/2) mice in different states of food activity (satiety, 24-h food deprivation, and cognitive load against the background of food deprivation). The hormonal response depended on food activity: the content of leptin, triiodothyronine, and testosterone decreased in hungry animals, while during cognitive load (learning), we observed a decrease in the concentrations of ghrelin, leptin, thyroxine, and testosterone. The exceptions were neuropeptide Y (its concentration increased in hungry animals) and corticosterone (its level remained unchanged). The use of hierarchical cluster analysis allowed identifying functional organization of the relationships within the hormonal ensemble that underwent plastic changes depending on the state of the organism. It was shown that the hormonal ensemble was system-organized in the form of a "core" that determines stability of the system and the "field", within which functional interactions of the hormones are preserved.

中文翻译：

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通过聚类分析棱镜的荷尔蒙集合的“行为”

研究了一组雄性 F1 (C57BL/6×DBA/2) 小鼠在不同食物活动状态（饱腹感、24 小时食物剥夺和食物剥夺背景下的认知负荷）中的血清激素浓度。激素反应取决于食物活动：饥饿动物的瘦素、三碘甲腺原氨酸和睾酮的含量降低，而在认知负荷（学习）期间，我们观察到生长素释放肽、瘦素、甲状腺素和睾酮的浓度降低。例外是神经肽 Y（其在饥饿动物中的浓度增加）和皮质酮（其水平保持不变）。层次聚类分析的使用允许识别激素集合内关系的功能组织，这些关系根据生物体的状态发生可塑性变化。