Eicosapentaenoic acid (EPA) and fucoxanthin, a carotenoid, provide a broad variety of health benefits in human nutrition. In this study, an up‐ and downstream process for the coproduction of EPA and fucoxanthin using the diatom Phaeodactylum tricornutum in flat‐panel airlift photobioreactors is proposed. The approach represents a promising alternative to conventional sources for both compounds, viz. marine fish and macroalgae. The productivity as well as the biomass‐specific product content were optimized during cultivation. Subsequently, both compounds were extracted, separated and purified using pressurized liquids.

中文翻译：

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EPA和褐藻黄质与角腐霉菌的联合生产–一种有前途的上下游加工方法

二十碳五烯酸（EPA）和岩藻黄质（类胡萝卜素）在人类营养中具有多种健康益处。在这项研究中，提出了在平板空运光生物反应器中使用硅藻Phaeodactylum tricornutum联合生产EPA和岩藻黄质的上下游工艺。该方法代表了这两种化合物的常规来源的有前途的替代方法。海鱼和大型藻类。在种植过程中优化了生产力以及特定于生物质的产品含量。随后，使用加压液体萃取，分离和纯化两种化合物。