The capability of synthetic pesticides to manage weeds, insect pests and pathogens in crops has diminished due to evolved resistance. Sustainable management is thus becoming more challenging. Novel solutions are needed and, given the ubiquity of biologically active secondary metabolites in nature, such compounds require further exploration as leads for novel crop protection chemistry. Despite improving understanding of allelochemicals, particularly in terms of their potential for use in weed control, their interactions with multiple biotic kingdoms have to date largely been examined in individual compounds and not as a recurrent phenomenon. Here, multi‐kingdom effects in allelochemicals are introduced by defining effects on various organisms, before exploring current understanding of the inducibility and possible ecological roles of these compounds with regard to the evolutionary arms race and dose–response relationships. Allelochemicals with functional benefits in multiple aspects of plant defence are described. Gathering these isolated areas of science under the unified umbrella of multi‐kingdom allelopathy encourages the development of naturally‐derived chemistries conferring defence to multiple discrete biotic stresses simultaneously, maximizing benefits in weed, insect and pathogen control, while potentially circumventing resistance. © 2020 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

中文翻译：

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综述：化感化学物质作为多国植物防御化合物：迈向综合方法

由于产生了抗药性，合成农药处理农作物中的杂草，害虫和病原体的能力已经减弱。因此，可持续管理变得更具挑战性。需要新颖的解决方案，并且鉴于自然界中具有生物活性的次生代谢产物的普遍存在，此类化合物作为新颖的作物保护化学的线索需要进一步探索。尽管对化感物质的理解有所改善，特别是在其用于控制​​杂草的潜力方面，但迄今为止，它们与多种生物界的相互作用在很大程度上已经在单个化合物中进行了研究，而不是作为一种复发现象进行。在这里，通过定义对各种生物的影响来引入化感物质中的多王国效应，在探索目前对这些化合物在进化军备竞赛和剂量反应关系方面的诱导性和可能的​​生态作用的理解之前。描述了在植物防御的多个方面具有功能益处的化感化学品。在多王国化病的统一保护下聚集这些孤立的科学领域，可促进自然衍生化学的发展，这些化学可同时防御多种离散的生物胁迫，从而在杂草，昆虫和病原体控制方面获得最大收益，同时有可能规避耐药性。©2020作者。在多王国化病的统一保护下聚集这些孤立的科学领域，可促进自然衍生化学的发展，这些化学可同时防御多种离散的生物胁迫，从而在杂草，昆虫和病原体控制方面获得最大收益，同时有可能规避耐药性。©2020作者。在多王国化病的统一保护下聚集这些孤立的科学领域，可促进自然衍生化学的发展，这些化学可同时防御多种离散的生物胁迫，从而在杂草，昆虫和病原体控制方面获得最大收益，同时有可能规避耐药性。©2020作者。John Wiley＆Sons Ltd代表化学工业协会出版的《害虫管理科学》。