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Biodegradable Films: Microporous Biodegradable Films Promote Therapeutic Angiogenesis (Adv. Healthcare Mater. 17/2020)
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2020-09-09 , DOI: 10.1002/adhm.202070059
Eseelle K. Hendow , Mehran Moazen , Francesco Iacoviello , Laurent Bozec , Caroline Pellet‐Many , Richard M. Day

In article number 2000806 by Richard M. Day and co‐workers, highly porous biodegradable films are prepared using thermally‐induced phase separation. In vivo implantation of the films into ischemic tissue stimulates increased expression of pro‐angiogenic growth factor genes. This provides a favourable local environment for neovascularization, increased tissue perfusion, and therapeutic angiogenesis in ischemic tissue. The findings pave the way to establishing new materials‐based strategies to achieve therapeutic angiogenesis.
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中文翻译:

可生物降解膜:微孔可生物降解膜促进治疗性血管生成(Adv。Healthcare Mater。17/2020)

理查德·戴(Richard M.Day)及其同事的文章编号2000806中,采用热诱导相分离技术制备了高度多孔的可生物降解薄膜。在体内将膜植入缺血组织可刺激促血管生成生长因子基因的表达增加。这为缺血性组织中的新血管形成,增加的组织灌注和治疗性血管生成提供了有利的局部环境。这些发现为建立新的基于材料的策略以实现治疗性血管生成铺平了道路。
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更新日期:2020-09-10
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