We have synthesized a series of quaternized imidazo[1,2-a]pyridines in three steps from commercially available reagents. These compounds exhibit blue fluorescence emission at around 425 nm with good quantum yields. In addition, one specific compound was found to work as not only a two- and three-photon excitable mitochondria imaging agent, but also a therapeutic agent upon continuous irradiation conditions.

中文翻译：

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二和三光子可激发的季铵化咪唑并[1,2-a]吡啶作为线粒体成像和有效的癌症治疗剂。

我们利用市售试剂分三步合成了一系列季铵化咪唑并[1,2- a ]吡啶。这些化合物在 425 nm 附近呈现蓝色荧光发射，具有良好的量子产率。此外，发现一种特定的化合物不仅可用作两光子和三光子可激发线粒体成像剂，而且在连续照射条件下也可用作治疗剂。