An Ir–oxalamidato complex in combination with a solid base (e.g., magnesium aluminometasilicate/Ca(OH)₂) significantly improved the catalyst productivity in α-alkylation of methyl ketones with primary alcohols. Optimization through systematic variation of the oxalamidato ligand led to a practical turnover number (TON) of 10 000–40 000.

中文翻译：

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Ir-oxalamidato /固体碱催化剂体系介导的醇与酮的高效α-烷基化

Ir-草胺酰胺配合物与固体碱（例如，铝硅酸镁/ Ca（OH）₂）结合可显着提高甲基酮与伯醇的α-烷基化反应的催化剂生产率。通过系统改变草酰胺的配体而进行的优化导致实际营业额（TON）为10,000至40,000。