Using dynamic polymers to achieve the morphology transformation of polymeric assemblies under different conditions is challenging. Herein, we reported diversiform shape transformation of multi-responsive polymer filaments, which were self-assembled by a new kind of amphiphilic block copolymer (PVEG-PVEA) possessing dynamic and reversible acylhydrazone bonds through reacting benzaldehyde-containing block copolymers poly(vinylbenzaldehyde)-b-poly(N-(4-vinylbenzyl)-N,N-diethylamine) (PVBA-PVEA) with acylhydrazine-modified oligoethylene glycol. It was found that the resulting amphiphilic and dynamic PVEG-PVEA was capable of hierarchically self-assembling into intriguing core-branched filaments in aqueous solution. Notably, the features of acylhydrazone bonds and PVEA block endow the filaments with multi-responsiveness including acid, base, and temperature, leading to the multiple morphological transformations under such stimuli. Moreover, the core-branched filaments would further transform into polymeric braided bundles driven by hydrogen-bonding interactions of amide bonds. It is noteworthy that both core-branched filaments and braided bundles made from polymers are quite rare. These diversiform polymeric assemblies and their morphological evolution were characterized by TEM, Cryo-TEM, SEM, and DLS. Finally, we used PVBA-PVEA as a platform to facilely prepare functional polymers, such as glycopolymers via the reaction of amino-containing sugars and aldehyde groups. The obtained glycopolymers self-assembled into glycofibers for the biomimicry of glycans via binding with lectins. These findings not only are conducive to understanding of the stimulated shape change process of dynamic polymeric assemblies in water but also provide a new method for the facile fabrication of smart and functional polymeric assemblies for different potential applications, such as biomimicry and targeted drug nanocarriers or delivery vehicles.

中文翻译：

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衍生自动态共价嵌段共聚物的聚合物长丝的多刺激​​触发形状转换。

使用动态聚合物在不同条件下实现聚合物组件的形态转变是具有挑战性的。在此，我们报道了多响应聚合物长丝的多种形状转变，这些长丝是通过一种新型两亲嵌段共聚物（PVEG-PVEA）通过含苯甲醛的嵌段共聚物聚（乙烯基苯甲醛）-反应而形成的，该两亲嵌段共聚物具有动态和可逆的hydr键。b-聚（N-（4-乙烯基苄基）-N，N-二乙胺）（PVBA-PVEA）与酰基肼改性的低聚乙二醇。已经发现，所产生的两亲性和动态的PVEG-PVEA能够在水溶液中分层自组装成吸引人的核心支化长丝。值得注意的是，酰hydr键和PVEA嵌段的特征赋予了长丝多种响应性，包括酸，碱和温度，从而在这种刺激下导致了多种形态转化。而且，芯支化的长丝将进一步转变成由酰胺键的氢键相互作用驱动的聚合物编织束。值得注意的是，由聚合物制成的纤芯支丝和编织束都非常少见。通过TEM，Cryo-TEM，SEM和DLS对这些多样的聚合物组装体及其形态演变进行了表征。最后，我们使用PVBA-PVEA作为平台，通过含氨基糖和醛基的反应轻松制备功能性聚合物，例如糖聚合物。所获得的糖聚合物通过与凝集素的结合而自组装成糖纤维，用于聚糖的仿生。这些发现不仅有助于了解水中动态聚合物组件的受激形状变化过程，而且为轻巧地制造适用于不同潜在应用（例如仿生和靶向药物纳米载体或递送）的智能和功能性聚合物组件提供了一种新方法。车辆。所获得的糖聚合物通过与凝集素的结合而自组装成糖纤维，用于聚糖的仿生。这些发现不仅有助于了解水中动态聚合物组件的受激形状变化过程，而且为轻巧地制造适用于不同潜在应用（例如仿生和靶向药物纳米载体或递送）的智能和功能性聚合物组件提供了一种新方法。车辆。所获得的糖聚合物通过与凝集素的结合而自组装成糖纤维，用于聚糖的仿生。这些发现不仅有助于了解水中动态聚合物组件的受激形状变化过程，而且为轻巧地制造适用于不同潜在应用（例如仿生和靶向药物纳米载体或递送）的智能和功能性聚合物组件提供了一种新方法。车辆。