Abstract

Introduction

ALSFRS-R is 12-item scale used to assess disability and to measure disease progression in ALS patients. The objective is to validate the Arabic version of ALSFRS-R based on the original English version. Methods and patients: This is a cross sectional study. ALSFRS-R was administered to 162 Egyptian patients with ALS after being translated in Arabic, and reapplied after 1 week. Patients were recruited from 2 centers: Neuromuscular unit, Ain Shams University hospitals and the specialized ALS clinic which is located at the international medical center (IMC). Results: No significant differences were found between the application and reapplication of the scale (p = 0.5). The linear regression and internal consistency that were measured by Pearson correlation and alpha Conbrach respectively were significant. Discussion: The Arabic version of the ALSFRS-R proposed by the current was proven to be reproducible and valid among Egyptian ALS patients. Thus, it will provide a useful tool for professionals to evaluate Arabic speaking patients in clinical practice and research.

中文翻译：

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修订后的肌萎缩侧索硬化功能评定量表 (ALSFRS-R) 的阿拉伯语适应和验证：埃及研究

摘要

介绍

ALSFRS-R 是 12 项量表，用于评估 ALS 患者的残疾和疾病进展。目标是验证基于原始英文版本的 ALSFRS-R 的阿拉伯文版本。方法和患者：这是一项横断面研究。ALSFRS-R 被翻译成阿拉伯语后用于 162 名埃及 ALS 患者，并在 1 周后重新应用。患者来自 2 个中心：神经肌肉科、艾因夏姆斯大学医院和位于国际医疗中心 (IMC) 的专门 ALS 诊所。结果：量表的应用和重新应用之间没有发现显着差异（p = 0.5）。分别用 Pearson 相关系数和 alpha Conbrach 测量的线性回归和内部一致性显着。讨论：目前提出的 ALSFRS-R 的阿拉伯语版本被证明在埃及 ALS 患者中是可重复和有效的。因此，它将为专业人员在临床实践和研究中评估讲阿拉伯语的患者提供有用的工具。