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Efficient extraction and purification of benzo[c]phenanthridine alkaloids from Macleaya cordata (Willd) R. Br. by combination of ultrahigh pressure extraction and pH‐zone‐refining counter‐current chromatography with anti‐breast cancer activity in vitro
Phytochemical Analysis ( IF 3.3 ) Pub Date : 2020-09-08 , DOI: 10.1002/pca.2990
Iftikhar Ali 1, 2 , Jingchao Li 1 , Li Cui 1 , Hongwei Zhao 1 , Qiuxia He 3 , Daijie Wang 1
Affiliation  

Macleaya cordata (Willd) R. Br. (Papaveraceae family) is a well‐known traditional Chinese medicine used to treat muscle pain, inflamed wounds, and bee bites. Benzo[c]phenanthridine alkaloids are the main active ingredients in M. cordata. In this work, sanguinarine and chelerythrine were efficiently extracted and purified by ultrahigh‐pressure extraction (UHPE) technique and pH‐zone‐refining counter‐current chromatography (PZRCCC) from M. cordata.

中文翻译:

从Macleaya cordata(Willd)R. Br。的苯并[c]菲啶生物碱的有效提取和纯化。通过超高压萃取和pH区域精制逆流色谱法结合体外抗乳腺癌活性

Macleaya cordata(Willd)R.Br. 罂粟科(Papaveraceae family)是一种著名的中药,用于治疗肌肉疼痛,发炎的伤口和蜜蜂叮咬。苯并[ c ^ ]菲啶生物碱是在其主要活性成分M.鱼腥草。在这项工作中,血根碱和白屈菜红被有效地提取并通过从超高压萃取(UHPE)技术和pH区域精制逆流色谱(PZRCCC)纯化M.鱼腥草
更新日期:2020-09-08
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