The synthesis of unprecedented BINOL‐derived cationic phosphonites is described. Through the use of these phosphanes as ancillary ligands in Au^I catalysis, a highly regio‐ and enantioselective assembly of appropriately designed alkynes into 1‐(aryl)benzo[5]carbohelicenes is achieved. The modular synthesis of these ligands and the enhanced reactivity that they impart to Au^I‐centers after coordination have been found to be the key features that allow an optimization of the reaction conditions until the desired benzo[5]helicenes are obtained with high yield and enantioselectivity.

中文翻译：

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使用BINOL衍生的阳离子亚膦酸酯作为辅助配体，对映选择性合成1-芳基苯并[5]螺旋。

描述了前所未有的BINOL衍生的阳离子亚膦酸酯的合成。通过在Au ^I催化中使用这些膦作为辅助配体，可以将适当设计的炔烃高度区域和对映选择性组装成1-（芳基）苯并[5]碳杂环丁烯。这些配体的模块化合成以及配位后赋予Au ^I中心的增强反应性是关键特征，可优化反应条件，直到以高收率获得所需的苯并[5]螺旋烯为止对映选择性。