Endometriosis is a chronic disease that commonly affects women in their reproductive age. It has been reported that the infertility due to endometriosis is largely caused by pelvic adhesion, oocyte damage, and so on. There are several causes of endometriosis including bacterial infections, immunological abnormalities, epigenetics, and aberrant DNA methylation. The natural killer (NK) cells present in the peritoneal fluid express CD16 and CD56. They also express NK cell inhibitory receptors and activating receptors and usually work to eliminate endometrial cells in the retrograde menstruation. However, in women with endometriosis, the changes in these receptors and production of cytokines by NK cells cause the onset and progression of endometriosis. In this review, we have focused on the role of NK cells in pelvic endometriosis and presented the immunological abnormalities in endometriosis including the possibility of future treatment.

中文翻译：

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盆腔子宫内膜异位症和自然杀伤细胞免疫。

子宫内膜异位症是一种慢性疾病，通常影响育龄妇女。据报道，子宫内膜异位症导致的不孕主要是由盆腔粘连、卵母细胞损伤等引起的。子宫内膜异位症有多种原因，包括细菌感染、免疫异常、表观遗传和异常的 DNA 甲基化。腹腔液中的自然杀伤 (NK) 细胞表达 CD16 和 CD56。它们还表达 NK 细胞抑制性受体和激活性受体，通常在逆行月经中起到清除子宫内膜细胞的作用。然而，在患有子宫内膜异位症的女性中，这些受体的变化和 NK 细胞产生的细胞因子会导致子宫内膜异位症的发生和发展。在这次审查中，