Indole and isoquinoline nuclei bearing homoallylic amine cores are abundant in several prominent alkaloids, including strychnine. A recent study by Snaddon et al. reports a modular, cooperative catalysis platform to access linear and branched homoallylic amines, thereby streamlining enantioselective access to stereochemically complex Strychnos and Chelidonium alkaloids.

中文翻译：

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基于催化的全合成的合作激活方式

带有均烯丙基胺核的吲哚和异喹啉核在包括士的宁在内的几种重要生物碱中含量很高。Snaddon等人的最新研究。报道了一种模块化的，协同的催化平台，以访问线性和支链的均烯丙基胺，从而简化了对立体化学复杂的马兜铃属和白屈菜碱生物碱的对映选择性访问。