Objectives Medicinal plants are used globally as alternative medicines in the management of a range of disease conditions and are widely accepted across differing societies. Ethiopia hosts a large number of plant species (>7000 higher plant species), of which around 12% are thought to be endemic, making it a rich source of plant extracts potentially useful for human health. The aim of this review is to evaluate Ethiopian medicinal plants for their anti-inflammatory, wound healing, antifungal or antibacterial activities. Methods and analysis The guidance of the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols (PRISMA-P) statement will be used. This review will consider all controlled studies of anti-inflammatory and wound healing properties (both in vivo and in vitro) and in vitro anti-infective properties of medicinal plants found in Ethiopia. Data sources will be EMBASE, PubMed/Medline, Scopus and Google Scholar. Guidance documents on good in vitro methods and checklists for reporting in vitro studies will be used for quality assessment of in vitro studies. The risk of bias tool for animal intervention studies (the SYRCLE RoB tool) will be used to assess the validity of studies. The main outcomes will be percent inhibition of inflammation, time of epithelisation and tissue tensile strength in wounds and microbial growth inhibition. Ethics and dissemination The findings of this systematic review will be disseminated by publishing in a peer-reviewed journal and via conference presentations. Ethical clearance was obtained from the Brighton and Sussex Medical School, Research Governance & Ethics Committee (RGEC) and Addis Ababa University, College of Health Science, Institutional Review Board. PROSPERO registration number This systematic literature review has been registered with PROSPERO (registration number CRD42019127471).

中文翻译：

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用于抗炎、伤口愈合或抗感染活动的埃塞俄比亚药用植物：系统文献回顾和荟萃分析方案

目标 药用植物在全球范围内被用作治疗一系列疾病的替代药物，并被不同社会广泛接受。埃塞俄比亚拥有大量植物物种（>7000 种高等植物物种），其中约 12% 被认为是地方性的，使其成为可能对人类健康有用的植物提取物的丰富来源。本综述的目的是评估埃塞俄比亚药用植物的抗炎、伤口愈合、抗真菌或抗菌活性。方法和分析 将使用系统评价和 Meta 分析协议 (PRISMA-P) 声明的首选报告项目指南。这篇综述将考虑在埃塞俄比亚发现的药用植物的抗炎和伤口愈合特性（体内和体外）和体外抗感染特性的所有对照研究。数据源将是 EMBASE、PubMed/Medline、Scopus 和 Google Scholar。关于良好体外方法的指导文件和体外研究报告清单将用于体外研究的质量评估。动物干预研究的偏倚风险工具（SYRCLE RoB 工具）将用于评估研究的有效性。主要结果将是炎症抑制百分比、上皮形成时间和伤口组织拉伸强度以及微生物生长抑制。伦理和传播 本系统评价的结果将通过在同行评审期刊上发表和通过会议报告进行传播。伦理许可获得了布莱顿和苏塞克斯医学院、研究治理与伦理委员会 (RGEC) 和亚的斯亚贝巴大学、健康科学学院、机构审查委员会。PROSPERO 注册号 本系统文献综述已在 PROSPERO 注册（注册号 CRD42019127471）。