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Multimodal imaging of thyroid cancer
Current Opinion in Endocrinology, Diabetes and Obesity ( IF 3.2 ) Pub Date : 2020-10-01 , DOI: 10.1097/med.0000000000000574
Katrin Brauckhoff , Martin Biermann

Purpose of review 

Thyroid cancer is the most common endocrine cancer in adults with rising incidence. Challenges in imaging thyroid cancer are twofold: distinguishing thyroid cancer from benign thyroid nodules, which occur in 50% of the population over 50 years; and correct staging of thyroid cancer to facilitate appropriate radical surgery in a single session. The clinical management of thyroid cancer patients has been covered in detail by the 2015 guidelines of the American Thyroid Association (ATA). The purpose of this review is to state the principles underlying optimal multimodal imaging of thyroid cancer and aid clinicians in avoiding important pitfalls.

Recent findings 

Recent additions to the literature include assessment of ultrasound-based scoring systems to improve selection of nodules for fine needle biopsy (FNB) and the evaluation of new radioactive tracers for imaging thyroid cancer.

Summary 

The mainstay of diagnosing thyroid cancer is thyroid ultrasound with ultrasound-guided FNB. Contrast-enhanced computed tomography and PET with [18F]-fluorodeoxyglucose (FDG) and MRI are reserved for advanced and/or recurrent cases of differentiated thyroid cancer and anaplastic thyroid cancer, while [18F]FDOPA and [68Ga]DOTATOC are the preferred tracers for medullary thyroid cancer.



中文翻译:

甲状腺癌的多模态成像

审查目的 

甲状腺癌是成年人中最常见的内分泌癌,发病率不断上升。甲状腺癌成像的挑战是双重的:将甲状腺癌与良性甲状腺结节区分开来,甲状腺结节良性结节在50年的人口中占50%。并正确校正甲状腺癌的分期,以在一次会议中促进适当的根治性手术。美国甲状腺协会(ATA)的2015年指南已详细介绍了甲状腺癌患者的临床管理。这篇综述的目的是阐明甲状腺癌最佳多模态成像的基本原理,并帮助临床医生避免重要的陷阱。

最近的发现 

文献的最新内容包括评估基于超声的评分系统,以改善对细针穿刺活检(FNB)结节的选择,以及评估对甲状腺癌成像的新型放射性示踪剂。

概要 

诊断甲状腺癌的主要方法是采用超声引导的FNB进行甲状腺超声检查。保留了[ 18 F]-氟脱氧葡萄糖(FDG)和MRI的增强对比计算机断层扫描和PET的功能,用于分化型甲状腺癌和间变性甲状腺癌的晚期和/或复发病例,而[ 18 F] FDOPA和[ 68 Ga] DOTATOC甲状腺髓样 的首选示踪剂。

更新日期:2020-09-08
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