Bone destruction is a remarkable feature of inflammatory arthritis. It remains unknown why arthritis associated with the systemic autoimmune/inflammatory condition systemic lupus erythematosus (SLE) does not result in erosion and destruction. We aimed to determine the role of autoantibody in the pathogenesis of non‐erosive arthritis in SLE.

中文翻译：

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狼疮 IgG 沉积导致关节炎，但通过竞争性占据 FcγRI 和减少 RANKL 信号传导抑制骨破坏

骨破坏是炎性关节炎的显着特征。与系统性自身免疫性/炎症性疾病系统性红斑狼疮 (SLE) 相关的关节炎为什么不会导致侵蚀和破坏仍然未知。我们旨在确定自身抗体在 SLE 非糜烂性关节炎发病机制中的作用。