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Cognition of the mothers of patients with Duchenne muscular dystrophy.
Muscle & Nerve ( IF 3.4 ) Pub Date : 2020-09-07 , DOI: 10.1002/mus.27057
Hasan Demirci 1 , Hacer Durmus 2 , Guven Toksoy 3 , Atilla Uslu 4 , Yesim Parman 2 , Hasmet Hanagasi 2
Affiliation  

Duchenne muscular dystrophy (DMD) has been found to be associated with cognitive impairment. However, few studies have addressed cognitive impairment among mothers of children with DMD. In the present study, the neuropsychological profiles of both carrier mothers (C‐Ms) and noncarrier mothers (NC‐Ms) were examined, and the findings were compared with healthy control mothers (HC‐Ms). There were 90 participants, consisting of 31 C‐Ms, 24 NC‐Ms, and 35 HC‐Ms, each of whom completed a neuropsychological test battery. C‐Ms had poorer cognition performance in attention, working memory, immediate verbal memory, visuospatial skills, and executive functions than NC‐Ms, and HC‐Ms. This study provides evidence that there may be cognitive impairment in mothers of patients with DMD. The cognitive impairment of C‐Ms has similarities to that seen in children with DMD.

中文翻译:

对杜氏肌营养不良患者母亲的认知。

已发现杜氏肌营养不良症(DMD)与认知障碍有关。但是,很少有研究解决DMD儿童母亲的认知障碍。在本研究中,检查了携带母亲(C-Ms)和非携带母亲(NC-Ms)的神经心理特征,并将研究结果与健康对照母亲(HC-Ms)进行了比较。有90名参与者,包括31名C-M,24名NC-M和35名HC-M,每个人都完成了一次神经心理测验。与NC-M和HC-M相比,C-M在注意力,工作记忆,即时言语记忆,视觉空间技能和执行功能方面的认知表现较差。这项研究提供了证据,表明DMD患者的母亲可能存在认知障碍。
更新日期:2020-09-07
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