Chemotherapy, combined with other treatments, is widely applied in the clinical treatment of cancer. However, deficiencies inherited from the traditional route of administration limit its successful application. With the development of nanotechnology, a series of smart nanodelivery systems have been developed to utilize the unique tumor environment (pH changes, different enzymes, and redox potential gradients) and exogenous stimuli (thermal changes, magnetic fields, and light) to improve the curative effect of anticancer drugs. In this review, endogenous and exogenous stimuli are briefly introduced. Among these stimuli, various redox‐sensitive linkages are primarily described in detail, and their application with self‐assembled nanoparticles is recounted. Finally, the application of redox‐responsive self‐assembled nanoparticles in cancer therapy is summarized.

中文翻译：

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氧化还原反应自组装纳米颗粒用于癌症治疗。

化学疗法与其他疗法的结合，被广泛应用于癌症的临床治疗。但是，从传统管理途径继承的缺陷限制了其成功应用。随着纳米技术的发展，已经开发了一系列智能纳米传递系统，以利用独特的肿瘤环境（pH变化，不同的酶和氧化还原电位梯度）和外源性刺激（热变化，磁场和光）来改善疗效抗癌药的作用。在这篇综述中，简要介绍了内源性和外源性刺激。在这些刺激中，主要详细描述了各种对氧化还原敏感的键，并叙述了它们在自组装纳米颗粒中的应用。最后，