Abstract

The results of studying piglets' cellular immunity in the postnatal period in an industrial pig-farming system have been reported. It is ascertained that the cellular immunity in piglets before colostrum intake is characterized by leukocytopenia, lymphocytopenia, T- and B-lymphocyte deficiencies and high ratios of theophylline-resistant (T-helpers) to theophylline-sensitive (T-suppressors) T cells, indicating the low suppressive activity of T lymphocytes. In 1-day-old piglets after colostrum intake and during the whole period of their growing under the sows, the increased counts of white-blood cells and lymphocytes, the T- and B-lymphocyte absolute counts, and T-helper cells, along with a lower count of T-suppressor cells and low T-to-B-cell ratios, indicating the predominant mechanisms of specific cellular defense, were recorded. A reduction in the counts of white-blood cells, lymphocytes, and T- and B-lymphocytes in piglets on the 14th day of life, when compared to the parameters measured on the seventh day of life, is caused by the decline in these cell’s supply via sow milk. A subsequent increase is associated with the activation of the piglets’ own immune system function, whose development is dependent on the effects of microbial contamination within the mucous membranes and the skin.

中文翻译：

---

产后早期仔猪细胞免疫状态

摘要

据报道，在工业化养猪系统中研究仔猪出生后细胞免疫的结果。可以确定，初乳摄入前仔猪的细胞免疫性表现为白细胞减少，淋巴细胞减少，T和B淋巴细胞缺乏，以及茶碱耐药（T辅助物）与茶碱敏感（T抑制物）T细胞的比例很高，表明T淋巴细胞的抑制活性较低。在初乳摄入后的1日龄仔猪以及在母猪生长的整个过程中，白血球和淋巴细胞计数，T和B淋巴细胞绝对计数以及T辅助细胞的数量增加。记录了较少的T抑制细胞数和较低的T到B细胞比值，表明了特异性细胞防御的主要机制。与出生后第7天测得的参数相比，出生后第14天的仔猪白血细胞，淋巴细胞以及T淋巴细胞和B淋巴细胞计数的减少是由于这些细胞的数量减少所致。通过母乳供应。随后的增加与仔猪自身免疫系统功能的激活有关，仔猪自身免疫系统的发育取决于粘膜和皮肤内微生物污染的影响。