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The Influence of the Cholesterol Level in Cells on Endovanilloid Cytotoxicity.
Doklady Biochemistry and Biophysics ( IF 0.8 ) Pub Date : 2020-09-07 , DOI: 10.1134/s1607672920040018
M G Akimov 1 , P V Dudina 1 , A M Gamisonia 1 , N M Gretskaya 1 , G N Zinchenko 1 , C C Mandal 2 , V V Bezuglov 1
Affiliation  

Abstract

The influence of the cellular cholesterol content on the cytotoxicity of endovanilloids acyldopamines was studied in MDA-MB-231 and MCF 10A cells. The activity of acyldopamines depends on the cellular cholesterol content, and a decrease in cholesterol content increases the cytotoxicity of acyldopamines.


中文翻译:

细胞中胆固醇水平对内皮素细胞毒性的影响。

摘要

在MDA-MB-231和MCF 10A细胞中研究了细胞胆固醇含量对内vanilloilloids acyldopamines细胞毒性的影响。酰基多巴胺的活性取决于细胞中胆固醇的含量,胆固醇含量的降低会增加酰基多巴胺的细胞毒性。
更新日期:2020-09-07
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