Abstract Two coordination polymers (CPs) based on Cu(II) of {[Cu(L)]·(CH3CN)}n (1) and {[Cu2(L)2(H2O)] 3H2O}n (2) (H2L = 5-(benzimidazole-1-yl)isophthalic acid) were prepared through the hydrothermal method and then characterized by elemental analysis and single-crystal X-ray diffraction. In addition, the magnetic performances of the complex 1 and the complex 2 were investigated, which revealed antiferromagnet interactions between the centers of the magnet. The preventative effect of the compounds on periodontitis was assessed, and the detailed mechanism was investigated. First, the inhibition of compound 1 or compound 2 against dental plaque formation was evaluated. Afterward, real-time RT-PCR was implemented to detect the expression of p53 and nf-κb in periodontal mucosal cells.

中文翻译：

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两种基于 Cu(II) 的配位聚合物：通过抑制牙菌斑形成对牙周炎的磁性和预防作用

摘要 {[Cu(L)]·(CH3CN)}n (1) 和 {[Cu2(L)2(H2O)] 3H2O}n (2) (H2L) 的两种基于 Cu(II) 的配位聚合物 (CPs) = 5-(苯并咪唑-1-基)间苯二甲酸)通过水热法制备，然后通过元素分析和单晶X射线衍射表征。此外，研究了配合物 1 和配合物 2 的磁性能，揭示了磁铁中心之间的反铁磁相互作用。评估了化合物对牙周炎的预防作用，并研究了详细的机制。首先，评价化合物1或化合物2对牙斑形成的抑制。然后，实施实时RT-PCR检测牙周黏膜细胞中p53和nf-κb的表达。